Caution: Do not use if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). Discontinue use and consult a healthcare practitioner if symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond 3 days. Consult a healthcare practitioner prior to use if you have nausea, fever, vomiting, bloody diarrhea or severe abdominal pain. Do not use if perma seal is missing.